Altered intrinsic properties of neuronal subtypes in malformed epileptogenic cortex

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Effects of resveratrol on intrinsic neuronal properties of CA1 pyramidal neurons in rat hippocampal slices

Introduction: Resveratrol (3,5,4-trihydroxystilbene) a non-flavonoid polyphenol found in some plants like grapes, peanuts and pomegranates, possesses a wide range of biological effects. Evidence indicates that resveratrol has beneficial effects on nervous system to induce neuroprotection. However, the cellular mechanisms of the effects are not fully determined. In the present study, the cellula...

متن کامل

Altered intrinsic neuronal interactions in the visual cortex of the blind.

In congenital blindness, the brain develops under severe sensory deprivation and undergoes remarkable plastic changes in both structure and function. Visually deprived occipital cortical regions are histologically and morphologically altered and exhibit a strikingly remodeled functional state: absolute levels of neural activity are heightened and are modulated by nonvisual sensory stimulation a...

متن کامل

Modulatory Effects of Memantine on Neuronal Response Properties in Rat Barrel Cortex

Introduction: Memantine as N-Methyl-D-aspartic acid (NMDA) receptor antagonist is used in some neurological disorders. It has been reported that memantine has modulatory effects on the somatosensory information processing in healthy subjects. This study investigated the effect of memantine on electrophysiological properties of barrel cortex neurons in male rats. Methods: Single unit recording ...

متن کامل

Altered intrinsic connectivity of the auditory cortex in congenital amusia.

Congenital amusia, a neurodevelopmental disorder of music perception and production, has been associated with abnormal anatomical and functional connectivity in a right frontotemporal pathway. To investigate whether spontaneous connectivity in brain networks involving the auditory cortex is altered in the amusic brain, we ran a seed-based connectivity analysis, contrasting at-rest functional MR...

متن کامل

Activity-Dependent Modification of Intrinsic Neuronal Properties

The processes that develop and maintain the intrinsic electrical properties of neurons are modeled by allowing the maximal strength of membrane conductances to be slowly varying functions of the intracellular calcium concentration. The resulting dynamic regulation of conductances allows model neurons to self-assemble their membrane currents and to react to and recover from external perturbation...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Brain Research

سال: 2011

ISSN: 0006-8993

DOI: 10.1016/j.brainres.2010.12.020